Zolvix™ Plus

Zolvix Plus is the only combination drench that contains 25 g/L monepantel. Monepantel’s unique mode of action provides efficacy against a broad spectrum of internal parasites of cattle and sheep, including single, double and triple resistant strains.

Key Product Benefits:

Unique Mode of Action
Broad Spectrum
Controls single, double and triple resistant strains of cattle and sheep roundworms

Pack Size

1L, 2.5L, 5L

Dosage

Administer orally, using an approved applicator, at a dose of 1 mL/10 kg body weight. Always read and follow the label directions.

Withholding periods

MEAT (SHEEP): 14 days

MEAT (CATTLE): 19 days

MILK (SHEEP): 35 days

MILK (CATTLE): 49 days

: Key Product Benefits:
Unique Mode of Action
Broad Spectrum
Controls single, double and triple resistant strains of cattle and sheep roundworms

Pack Size
1L, 2.5L, 5L

Dosage
Administer orally, using an approved applicator, at a dose of 1 mL/10 kg body weight. Always read and follow the label directions.
Withholding periods
MEAT (SHEEP): 14 days
MEAT (CATTLE): 19 days
MILK (SHEEP): 35 days
MILK (CATTLE): 49 days

Why Choose Zolvix™ Plus?

Increasing levels of resistance to the older classes of anthelmintics has the potential to cost sheep farmers thousands of dollars in lost productivity every year.^3,4 A highly effective drench, Zolvix Plus contains the novel anthelmintic monepantel, Zolvix Plus should be considered as the first choice for quarantine, knock out or exit drench or where the resistance status of parasites is not known.

Unique Mode of Action

A unique combination drench that provides the effectiveness of monepantel with abamectin.

Monepantel is the only member of the amino-acetonitrile derivative (AAD) class of anthelmintics.

Broad Spectrum

With its broad-spectrum activity, Zolvix Plus controls all economically important roundworm parasites of sheep and cattle, including adult and immature L4 stages. Refer to label for more information.^1,2

Decreased Risk of Resistance

Zolvix Plus controls single, double and triple resistant strains of cattle and sheep roundworms. Zolvix Plus is ideal for use if the resistance status of the flock or herd is unknown.

Zolvix™ Plus Important Information

Find the information you need to incorporate Zolvix™ Plus into your sheep management program. Always read and follow the label directions.

DESCRIPTION

DIRECTIONS FOR USE

WITHHOLDING PERIODS

LABEL AND REFERENCES

ZOLVIX™ PLUS

Broad Spectrum Oral Anthelmintic for Sheep and Cattle

ACTIVE CONSTITUENTS: 25 mg/mL monepantel and 2 mg/mL Abamectin. Monepantel is a member of the class of anthelmintics called the Amino-Acetonitrile Derivatives (AADs) while abamectin is a member of the Macrocyclic Lactone (ML) class of anthelmintics.

Zolvix PLUS is effective for the treatment and control of sensitive strains of nematodes (roundworms), including nematodes that have single, dual or triple resistance to macrocyclic lactones (including moxidectin resistant strains), benzimidazoles (white drenches), imidazothiazoles (levamisole, clear drench) in sheep, beef cattle and non-lactating dairy cattle and morantel (clear drench) and salicylanilide (e.g. closantel)-resistant strains, in sheep.

Zolvix PLUS is also effective against AAD-sensitive immature (L4) stages of Haemonchus contortus and Teladorsagia circumcincta in sheep where a combination of a macrocyclic lactone and derquantel is less effective.

DOSAGE AND ADMINISTRATION

The product is NOT TO BE USED in sheep less than 15 kg of bodyweight or 3 months of age.

The product is NOT TO BE USED in cattle less than 100 kg of bodyweight or 16 weeks of age.

Zolvix PLUS is a ready-to-use oral solution. A representative sample of animals should be weighed before treatment. Dose the animals to the heaviest liveweight in each group. DO NOT under dose. Where there is a large variation in weight within the group, dose should be based on the label directions for each weight range.

Drafting into two or more lines may be appropriate, to avoid excessive overdosing.

A correct drenching technique is recommended; carefully place the drench gun nozzle in the side of the mouth and over the back of the tongue before delivering the dose.

Check dose and drench gun before treatment commences. Drench animals orally using an Elanco recommended drench gun.

Maintain applicator gun carefully to ensure accurate dosage. After use, clean gun by flushing with warm, soapy water. Rinse with cold water.

SHEEP

The dose for sheep and lambs is 0.5 mL/5 kg (1 mL/10 kg), equivalent to 2.5 mg monepantel/kg and 0.2 mg abamectin/kg bodyweight.

CATTLE

The dose for cattle is 5 mL/50 kg (1 mL/10 kg) (equivalent to 2.5 mg monepantel/kg and 0.2 mg abamectin/kg bodyweight).

By law the user must take due care, obtaining expert advice, when necessary, to avoid unnecessary pain and distress when using the product other than as directed on the label.

MEAT WHP (SHEEP): Sheep producing meat or offal for human consumption must not be sold for slaughter either during treatment or within 14 days of the last treatment.

MEAT WHP (CATTLE): Cattle producing meat or offal for human consumption must not be sold for slaughter either during treatment or within 19 days of the last treatment.

MILK WHP (SHEEP): Milk intended for sale for human consumption must be discarded during treatment and for not less than 35 days following the last treatment.

MILK WHP (CATTLE): Milk intended for sale for human consumption must be discarded during treatment and for not less than 49 days following the last treatment. If calving occurs within 7 weeks of the last treatment, milk must not be processed for human consumption until 7 weeks following last treatment has passed.

Product Label

By law the user must take due care, obtaining expert advice when necessary, to avoid unnecessary pain and distress when using the product other than as directed on the label. Read label and obtain special instructions before use. Do not handle until all safety precautions have been read and understood.

Download:

Zolvix Plus 5L Front Label.pdf

Zolvix Plus 5L Back Label.pdf

First Aid: If exposed or you feel unwell contact the Poisons Centre 0800 POISON (0800 764766) or a doctor immediately.

References

1. Refer to registered label.

2. Hosking, B.C. et al. (2010). A pooled analysis of the efficacy of monepantel, an amino-acetonitrile derivative against gastrointestinal nematodes of sheep. Parasitol Res 106:529-532.

Copyright

Zolvix™ Plus Broad Spectrum Oral Anthelmintic for Sheep and Cattle is registered under the ACVM Act 1997 No: A011107.

Zolvix, is a trademark of Elanco. Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates. Elanco New Zealand, 106 Wiri Station Road, Manukau, Auckland 2104.

Safety Data Sheet (SDS)

The SDS for Zolvix™ features first aid measures, handling and storage instructions including recommended PPE, and transport advice. Read thoroughly before use of the product.

Zolvix™ SDS