Denagard® (Tiamulin hydrogen fumarate)

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Denagard® (Tiamulin hydrogen fumarate)

Denagard® 10 Premix: For control and treatment of swine dysentery (SD) associated with Brachyspira hyodysenteriae* and control of ileitis associated with Lawsonia intracellularis.* +CTC: For control of SD associated with B. hyodysenteriae* and for treatment of swine bacterial enteritis caused by E. coli. Denagard® LC: Treatment of SD associated with B. hyodysenteriae and swine pneumonia due to Actinobacillus pleuropneumoniae (APP)*

Reliable Enteric Products

  • Dependable.
  • Effective.

Denagard + CTC Trial Results*1

As a result of controlling respiratory and enteric disease**:

Lower overall incidence of disease

Reduced SRD, diarrhea and lameness resulting in reduced treatments

Increased Activity

Against labeled pathogens and enlarged the spectrum of control

Health Impact on Growth**

3.5 lbs heavier final weight and 1.4% better ADG

Reliable Enteric Disease Treatment

  • Effectively controls SD associated with Brachyspira hyodysenteriae, a highly contagious, difficult to control and slow immunity generating disease2 and ileitis associated with Lawsonia intracellularis, a leading enteric disease in the U.S.
  • Mitigate these disease challenges with whole-herd treatment through pulse dosing or continuous medication.

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Denagard Premix Product Label

Read the full label for important use and safety information

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Our portfolio offers solutions that manage disease challenges and mitigate mortality to optimize health.

Swine Intestinal Integrity

Intestinal Integrity

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The label contains complete use information, including cautions and warnings. Always read, follow and understand the label and use directions.

Denagard® 10 Premix:

INDICATIONS:

  • For control of swine dysentery associated with Brachyspira hyodysenteriae susceptible to Tiamulin.
  • For treatment of swine dysentery associated with Brachyspira hyodysenteriae susceptible to Tiamulin.
  • For control of porcine proliferative enteropathies (ileitis) associated with Lawsonia intracellularis susceptible to Tiamulin.
  • + CTC: For control of swine dysentery associated with Brachyspira hyodysenteriae susceptible to Tiamulin and for treatment of swine bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis sensitive to chlortetracycline and treatment of bacterial pneumonia caused by Pasteurella multocida sensitive to chlortetracycline.

DIRECTIONS FOR USE

For treatment of swine dysentery associated with Brachyspira hyodysenteriae susceptible to Tiamulin:

  • Feed 200 g/ton for 14-days for treatment (7-day withdrawal).

For control of porcine proliferative enteropathies (ileitis) associated with Lawsonia intracellularis:

  • Feed 35 g/ton for not less than 10 days (2-day withdrawal).

For control of swine dysentery associated with Brachyspira hyodysenteriae susceptible to Tiamulin:

  • Feed 35 g/ton continuously as sole ration (2-day withdrawal).

Using Denagard alone does not require a Veterinary Feed Directive (VFD). Using Denagard + CTC does require a VFD.

  • Feed 35 g/ton of Denagard + 400 g/ton (10 mg/lb body weight in daily divided doses) CTC for 14 days.

IMPORTANT SAFETY INFORMATION

  • Keep out of reach of children.
  • Avoid contact with skin. Direct contact with skin or mucous membranes may cause irritation.

CAUTION: Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. Do not feed undiluted. Do not use in feeds for animals other than swine.

  • The effects of Tiamulin on swine reproductive performance, pregnancy and lactation have not been determined.
  • Swine being treated with Denagard (Tiamulin) should not have access to feeds containing polyether ionophores (e.g., lasalocid, monensin, narasin, salinomycin and semduramicin) as adverse reactions may occur. If signs of toxicity occur, discontinue use.

Denagard® LC

INDICATIONS:

  • Treatment of swine dysentery associated with Brachyspira hyodysenteriae and swine pneumonia due to Actinobacillus pleuropneumoniae, susceptible to Tiamulin.

DIRECTIONS FOR USE:

  • For treatment of swine dysentery, utilize Denagard LC in drinking water at 3.5 mg/lb for five consecutive days.
  • For treatment of swine pneumonia, utilize Denagard LC in drinking water at 10.5 mg/lb for five consecutive days.

IMPORTANT SAFETY INFORMATION:

  • Keep out of reach of children.
  • Avoid direct contact with the skin. Direct contact with skin or mucous membranes may cause irritation.
  • Withdraw medicated water 3 days before slaughter after treatment at 3.5 mg/lb and 7 days before slaughter following treatment at 10.5 mg/lb.

CAUTION: For use in drinking water of swine only - Not for use in humans.

  • Prepare fresh medicated water daily. Use as the only source of drinking water for 5 days.
  • The effects of Tiamulin on swine reproductive performance, pregnancy and lactation have not been determined.
  • Swine being treated with Denagard (Tiamulin hydrogen fumarate) should not have access to feeds containing polyether ionophores (e.g. lasalocid, monensin, narasin, salinomycin and semduramicin) as adverse reactions may occur.