Zelnate® DNA lmmunostimulant

Zelnate® DNA lmmunostimulant
An innovative technology that jump-starts the animal's immune system response at times of stress, resulting in an improved ability to fight Bovine Respiratory Disease (BRD).
Dosage and Pack Size
Zelnate can be administered intramuscularly or intranasally. Inject 2 mL intramuscularly at the time of, or within 24 hours after, a perceived stressful event. Alternatively, spray 2 mL into one nostril using an atomization tip attached to the syringe. Zelnate is available in 10 and 50 dose packs.
First-of-its-kind Zelnate® DNA lmmunostimulant aids in the treatment of BRD due to Mannheimia haemolytica when administered at the time of or, within 24 hours after, a perceived stressful event in cattle 4 months of age and older.
How it works:
- When a stressful event like shipping, movement or a known BRD exposure occurs, Zelnate can be administered via intramuscular injection or intranasally
- Following administration, the unique DNA liposome complex in Zelnate stimulates the innate immune system in cattle
- The innate immune system has been shown to provide a rapid, potent and broad protective response to infectious agents
- Zelnate contains no antibiotics and no preservatives, and can be used in natural programs
Why choose Zelnate?
Zelnate is a novel, first-of-its-kind immunostimulant that jump-starts the animal's immune system to help fight BRD.
The unique DNA liposome complex in Zelnate stimulates the innate immune system in cattle. Zelnate contains no antibiotics or preservatives, giving natural beef programs an effective tool to manage BRD.
In six studies, Zelnate was shown to significantly reduce mortality due to BRD from 4.45% to 3.5%, or a relative change of 20.83%, when compared to the control group.2
When compared to antimicrobial metaphylaxis therapy in cattle at medium risk of developing BRD, Zelnate performed in a comparable fashion and was observed to be non-inferior to antimicrobials.1
Zelnate can be administered intramuscularly or intranasally using an atomization tip attached to the syringe.
How to mix Zelnate
For administration directions, click on the How to administer tab below.
Once mixed, Zelnate must be administered within 24 hours. After 24 hours, the product is no longer viable.
Part of the Elanco BRD portfolio
Zelnate is part of a broad BRD management portfolio that includes vaccines and anti-infectives and is supported by Elanco technical consultants who can help your business maximize the product’s value.
Zelnate product information
Click to download Zelnate® DNA lmmunostimulant product label.
Click to download Zelnate® Tech Sheet.
Zelnate is indicated for the treatment of BRD due to Mannheimia haemolytica in cattle 4 months of age or older, when administered at the time of or after 24 hours after a perceived stressful event.
Do not administer within 21 days of slaughter. Do not mix with other products, except as specified on this label. This product has not been tested in pregnant animals.
Zelnate is based on technology developed by Juvaris BioTherapeutics and is patent-protected. Animal health applications are being developed exclusively under the rights of Elanco and are protected by patents.
Zelnate is a trademark of Elanco or its affiliates.