BRD IS AN RBD
BRD is an RBD (really big deal) and a big challenge. Commonly known as shipping fever or pneumonia, BRD is one of the most pervasive diseases in the cattle industry. Learn how you can prevent, control and treat BRD with Elanco.
Breathe Easier. We've got you covered.
Unpredictable weather, nutritional challenges and transportation stress on your herd may not always be in the realm of your control. But the cost to cattle producers — about $1 billion annually1 — doesn't go unnoticed. With our portfolio that is 40 years in the making, you can choose what tools you use to control and treat BRD in your herd.
Prevent BRD
BRD-causing pathogens are both viral and bacterial. Vaccination that protects against both is an important part of a BRD-prevention strategy that prepares each animal's immune system.
Elanco BRD vaccines help protect against the leading causes of BRD so cattle stay healthy and productive.

NUPLURA® PH and NUPLURA PH+
NUPLURA PH gives the fastest protection in as few as 10 days against Mannheimia haemolytica — the bacterial pathogen responsible for most cases of BRD.² NUPLURA PH+ combines the protection of NUPLURA PH and Titanium® in one vaccine, giving herds fast, smooth and powerful protection against Mannheimia haemolytica, BVD Type 1 and 2 and IBR — leading causes of BRD.

Titanium®
Provides important protection as a modified live virus (MLV) vaccine against up to 10 respiratory and reproductive pathogens. Used as the foundation of a vaccine program for lifetime immunity, trust Titanium to set your herd up for protection without post-vaccinal stress.*³,⁴

Vira Shield®
Delivers Control Without Complication® against up to 13 respiratory and reproductive pathogens. Stress less with Vira Shield as it doesn’t negatively impact reproductive rates so you can see more calves and fewer open animals.⁵
Treat and Control BRD
Even with excellent management, genetics and vaccination, antibiotics may be necessary for BRD treatment and control. Antibiotic selection is an important choice because BRD has a broad range of causative pathogens.
That's why producers can count on the broad Elanco antibiotic portfolio. With a variety of products for control and treatment, producers can choose from multiple modes of action to select the right product, at the right time, to help keep their cattle productive and healthy.

Pradalexᵀᴹ (pradofloxacin injection)
Pradalex is an innovative third generation fluoroquinolone antibiotic for the treatment of bovine respiratory disease (BRD).

Baytril® 100 (enrofloxacin)
Baytril 100 is a proven tool for BRD treatment and control in beef and non-lactating dairy.

Micotil® (tilmicosin injection)
A proven, long-lasting BRD treatment that offers an effective, flexible dose range for both metaphylaxis and individual pull-and-treat therapy.
Increxxa™ (tulathromycin injection)
The macrolide antibiotic you can trust to help your cattle breathe easier while balancing your budget.

Tylan® Injection (tylosin injection)
Treats BRD in high-risk cattle as well as treats foot rot in beef and non-lactating dairy cattle.

FOR ALL PRODUCTS: The label contains complete use information, including cautions and warnings. Always read, understand, and follow the label, and use directions.
Micotil
Before using Micotil 300, it is important to read the entire product insert, including the boxed human warning. For full prescribing information call 1 888 545 5973 or visit www.elancolabels.com/us/micotil-300.
HUMAN WARNING: Not for human use. Injection of this drug in humans has been associated with fatalities. Keep out of reach of children. Administer only with a tube-fed safety syringe. Do not use in automatically powered syringes, single-use syringes, or other delivery devices. Exercise extreme caution to avoid accidental self-injection. In case of human injection, consult a physician immediately and apply ice or cold pack to injection site while avoiding direct contact with the skin. Emergency medical telephone numbers are 1-800-722-0987 or 1-800-428-4441. Avoid contact with skin, eyes, or mucous membranes.
Micotil is available only by prescription. Micotil must be used with the quick-fit connector and tube-fed safety syringe included to avoid accidental self-injection. Contact Elanco or your distributor for this equipment if needed. For subcutaneous injection in cattle and sheep only; do not administer intravenously. Injection of this antibiotic has been shown to be fatal in swine and non-human primates and may be fatal in horses, goats, and other species. Not for use in use in lactating dairy cattle 20 months of age or older. Use in lactating dairy cattle or sheep may cause milk residues. Injection site swelling and inflammation, lameness, collapse, anaphylaxis/anaphylactoid reactions, decreased food and water consumption, and death have been reported in cattle. Micotil has a pre-slaughter withdrawal time of 42 days. See package insert for full prescribing information.
Baytril 100
BAYTRIL 100 CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian and prohibits the extra-label use of this drug in food-producing animals.
Not for human use. Keep out of reach of children. Avoid contact with eyes and skin. Individuals with a history of hypersensitivity to quinolones should avoid this product. Not for use in female dairy cattle 20 months of age or older, including dry dairy cows, and veal calves; a withdrawal period has not been established for this product in pre-ruminating calves. Quinolone-class drugs should be used with caution in animals with known or suspected Central Nervous System (CNS) disorders. Baytril 100 has a pre-slaughter withdrawal time of 28 days for cattle. See package insert for additional safety information.
Increxxa
Increxxa is available only by prescription. Not for human use. Keep out of reach of children. Do not use in animals previously found to be hypersensitive to the drug. Not for use in chickens or turkeys. Do not use in female dairy cattle 20 months of age or older, including dry dairy cows. Injection site reactions and anaphylaxis/anaphylactoid reactions have been reported in cattle. Increxxa has a pre-slaughter withdrawal time of 18 days for cattle. See package insert for full prescribing information.
Pradalex
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian and prohibits the extra-label use of this drug in food-producing animals. To ensure responsible antimicrobial drug use, use of pradofloxacin should be limited to treatment of bovine respiratory disease (BRD) in cattle only after consideration of other non-fluoroquinolone therapeutic options.
Not for use in humans. Keep out of reach of children. Avoid contact with eyes and skin. Individuals with a history of hypersensitivity to quinolones should avoid this product. Not for use in animals intended for breeding greater than 1 year of age. Not for use in beef calves less than 2 months of age, dairy calves and veal calves; a withdrawal period has not been established for this product in pre-ruminating calves. Quinolones should be used with caution in animals with known or suspected central nervous system (CNS) disorders. Mild to moderate inflammatory changes of the injection site may be seen in cattle treated with Pradalex. Pradalex has a pre-slaughter withdrawal time of 4 days for cattle. See package insert for additional safety information.
Tylan Injection
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
WARNING: NOT FOR HUMAN USE. KEEP OUT OF REACH OF CHILDREN.
Do not use Titanium® BRSV 3, Titanium® 3 LP, Titanium® 3, Titanium® IBR LP and Titanium® IBR in pregnant cows or in calves nursing pregnant cows. Abortions may result
Increxxa, Micotil, Nuplura, Titanium, Tylan, Vira Shield, Elanco, and the diagonal bar logo are trademarks of Elanco or its affiliates.
Baytril is sold by Elanco or its affiliates and is not a Bayer product. The Baytril trademark is owned by Bayer and used under license.
