Pradalexᵀᴹ (pradofloxacin injection)
Pradalexᵀᴹ (pradofloxacin injection)
Pradalex is an innovative third generation fluoroquinolone antibiotic for the treatment of bovine respiratory disease (BRD). Pradofloxacin, the active ingredient in Pradalex, uniquely features two modes of action yielding improved potency and a broader spectrum of activity relative to other fluoroquinolone antibiotics, enabling your cattle to get back to health sooner.¹
Vial Size
100 ml vial ; 250 ml vial
2.3 mL/100 lb
- Concentration dependent antibiotic with a dual mode of action that kills bacteria before they can replicate
- Highly potent and rapidly absorbed, delivering faster* BRD treatment than traditional time-dependent antibiotics
- Quickly eliminated from the body, resulting in a shorter withdrawal period, less potential impact on the microbiome, and reduced chance for resistance development
- Convenient, single dose, low-volume antibiotic with best-in-class syringeability
- Indicated for the treatment of BRD associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis
*Clinical relevance unknown.
Effective BRD Treatment
Mannheimia haemolytica
Pasteurella multocida
Histophilus somni
Mycoplasma bovis
Mode of Action Matters
Pradalex is different from other fluoroquinolone antibiotics used to treat BRD because it has equal affinity for both enzymes responsible for DNA replication in both gram-negative and gram-positive organisms.
Pradalex is the most potent fluoroquinolone antibiotic. Because Pradalex is bactericidal and targets DNA, it kills bacteria in both the resting and growth phases of bacterial development.2,3 These features combined with fast absorption and rapid elimination work together to reduce the risk of developing resistant bacteria and make Pradalex an excellent choice as a treatment antibiotic.
Why Choose Pradalex?
Pradalex combines rapid absorption and distribution with broad spectrum efficacy to reliably kill the primary BRD pathogens.
Reaches maximum therapeutic concentration levels in the plasma in 45 minutes
Kills targeted bacteria at achievable concentrations within 5 minutes
Spends only 8 hours in the mutant selection window (MSW)
Quickly excreted from the body allowing for a 4-day slaughter
Back to Health Fast
Learn about the science behind Pradalex, and how it helps your herd get back to health.
Speed Video
Learn how Pradalex can help your cattle get back to health sooner.
Efficacy Video
Learn more about the efficacy of Pradalex for BRD.
Antimicrobial Resistance Video
See how Pradalex reduces the risk of selecting for antimicrobial resistance.
To learn more about Pradalex, contact your herd health veterinarian or Elanco representative.
To find a representative, please call 1-800-364-2014 or go to our sign-up form below.
Important Information
Indications
Administration
Precautions
Storage
Indications
Cattle: Pradalex is indicated for the treatment of BRD associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis in cattle intended for slaughter (beef calves 2 months of age and older, growing beef steers, growing beef heifers, and beef bulls intended for slaughter), and in cattle intended for breeding less than 1 year of age (replacement beef and dairy heifers less than 1 year of age and beef and dairy bulls less than 1 year of age). Not for use in cattle intended for breeding 1 year of age and older (replacement beef and dairy heifers 1 year of age and older, beef and dairy bulls 1 year of age and older, and beef and dairy cows), beef calves less than 2 months of age, dairy calves, and veal calves.
Downloadable Resources
Looking for more information? Access these resources or contact your Elanco representative.
To find a representative, please call 1-800-364-2014
The label contains complete use information, including cautions and warnings. Always read, follow and understand the label and use directions
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Not for use in humans. Keep out of reach of children. Avoid contact with eyes and skin. Individuals with a history of hypersensitivity to quinolones should avoid this product. Not for use in animals intended for breeding greater than 1 year of age because the effects of Pradalex on bovine reproductive performance, pregnancy, and lactation have not been determined. Not for use in beef and dairy calves less than 2 months of age, and veal calves; a withdrawal period has not been established for this product in pre-ruminating calves. Quinolones should be used with caution in animals with known or suspected central nervous system (CNS) disorders. Mild to moderate inflammatory changes of the injection site may be seen in cattle treated with Pradalex. See package insert for additional safety information.
INDICATIONS: Pradalex is indicated for the treatment of BRD associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis in cattle intended for slaughter (beef calves 2 months of age and older, growing beef steers, growing beef heifers, and beef bulls intended for slaughter), and in cattle intended for breeding less than 1 year of age (replacement beef and dairy heifers less than 1 year of age and beef and dairy bulls less than 1 year of age). Not for use in cattle intended for breeding 1 year of age and older (replacement beef and dairy heifers 1 year of age and older, beef and dairy bulls 1 year of age and older, and beef and dairy cows), beef calves less than 2 months of age, dairy calves, and veal calves.
ADMINISTRATION: Administer once as a subcutaneous injection at a dosage of 10 mg/kg (2.3 mL/100 lb) body weight. Do not inject more than 15 mL per subcutaneous injection site.
Pradalex, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.
