The Titanium® vaccine line delivers effective, proven protection against Bovine Respiratory Disease (BRD) pathogens like Bovine Viral Diarrhea (BVD) Type 1 and 2¹﹐² without impacting feed intake³ or milk production⁴ and results in little to no post-treatment side effects*⁵-⁷. Keep your cattle on track with health management solutions that don’t interrupt your day-to-day operations or affect your bottom line.

Key Benefits:

  • Immunity against up to 11 respiratory and reproductive pathogens
  • Multiple combinations to protect the herd against what matters most
  • Research demonstrates protection against BVD Type 1 and 2¹,² and IBR8

Powerful Combinations To Keep Your Herd on Track

Titanium is available in multiple combinations to suit your herd. Choose the option that provides protection for the respiratory and reproductive pathogens that your operation faces.

Titanium CombinationsIBRIBR LP3BRSV 33 LP4 L555 L5 HB
BVD Type 1

BVD Type 2




L. canicola

L. grippotyphosa

L. hardjo-prajitno

L. icterohaemorrhagiae

L. pomona

L. hardjo-bovis

MLV = Modified Live Virus
L. hardjo-bovis cross protection provided through L. hardjo-prajitno antigen

To learn more about how Titanium delivers the right protection at the right time, contact your herd health veterinarian or Elanco representative. To find a representative, please call 1-800-364-2014.

Important Information

Learn about Titanium indications, directions and safety precautions.


Titanium 5 L5 HB contains BVD Type 1 and 2 and is recommended for the vaccination of healthy cows and heifers, no less than 30 days prior to breeding, as an aid in the prevention of disease caused by Bovine Viral Diarrhea (BVD) Type 1 and 2, Infectious Bovine Rhinotracheitis (IBR), Bovine Parainfluenza3 (PI3), Bovine Respiratory Syncytial Virus (BRSV) and Leptospira borgpetersenii serovar hardjo-bovis and L. canicola, L. grippotyphosa, L. hardjo, L. icterohaemorrhagiae and L. pomona.

Titanium 5 L5 HB may be administered to pregnant cattle provided they were vaccinated according to label directions with Titanium 3, Titanium 4 L5, Titanium 5 or Titanium 5 L5 HB 30 to 60 days prior to breeding. Titanium 5 L5 HB may also be administered to calves nursing pregnant cows provided their dams were vaccinated as described above.

For all vaccine products: The label contains complete use information, including cautions and warnings. Always read, understand and follow the label and use directions.