NUPLURA® PH+
NUPLURA® PH+
NUPLURA® PH+ combines the protection of NUPLURA® PH and Titanium® in one vaccine, giving herds fast, smooth and powerful protection against the leading cause of Bovine Respiratory Disease (BRD). It provides flexible protection against both bacterial and viral pathogens causing BRD¹, so your animals have the right protection right when they need it.
Dosage
2 mL
Key Benefits:
- NUPLURA provides protective immunity against M. haemolytica in as few as 10 days after vaccination
- It’s easy on cattle with minimal reactivity, including few adverse events or transient injection site swelling2
- NUPLURA uses recombinant leukotoxoid technology and outer membrane proteins, two virulence factors for protection by advanced technology
- NUPLURA PH+5 delivers additional protection against Infectious Bovine Rhinotracheitis (IBR) and BVD Type 1 and 2, BRSV and PI3
- NUPLURA PH+3 delivers additional protection against Infectious Bovine Rhinotracheitis (IBR) and BVD Type 1 and 2
- In one vaccination, NUPLURA PH+ combines the rapid immune response of NUPLURA PH with the powerful viral protection of Titanium
Why Choose NUPLURA?
NUPLURA is the fastest-acting M. haemolytica vaccine available, providing rapid protection against the leading causes of BRD. NUPLURA uses recombinant leukotoxoid technology and outer membrane proteins for a strong immune response.
Provides protective immunity in as few as 10 days.
Gentle on calves as young as 28 days.
Provides additional protection against IPR, BVD (Types 1 & 2), BRSV, PI3, and Mannheimia haemolytica.
Deliver The Right Protection When It Matters Most
NUPLURA delivers the fastest protection against M. haemolytica, the leading cause of BRD.
Now add smooth and powerful, and it’s check, check and check.
NUPLURA PH | NUPLURA PH+5 | Pyramid 5 +Presponse | NUPLURA PH+3 | PYRAMID 3 | |
Safe Age-proven safe for use | 28 days | 28 days | No claim | 28 days | No claim |
Smooth Uses only outer membrane proteins, reducing harmful endotoxins | ✓ | ✓ | ✓ | ||
Powerful Recombinant leukotoxoid for a strong immune response | ✓ | ✓ | ✓ | ||
Respiratory Coverage Effective against the following causes of BRD: | |||||
M. haemolytica | ✓ | ✓ | ✓ | ✓ | ✓ |
BVD Type 1 | ✓ | ✓ | ✓ | ✓ | |
BVD Type 2 | ✓ | ✓ | ✓ | ✓ | |
IBR | ✓ | ✓ | ✓ | ✓ | |
BRSV | ✓ | ✓ | |||
PI3 | ✓ | ✓ |
The Dual Defense Difference
The advanced molecular science behind NUPLURA can be complex, but the difference is clear. NUPLURA is the only M. haemolytica and BRD prevention vaccine that uses recombinant technology and outer membrane proteins (OMPs)—two virulence factors for protection by advanced technology. The result is fast, smooth protection against BRD that’s easy on cattle with minimal reactivity.2
To learn more about how NUPLURA delivers a fast, smooth, powerful and convenient vaccination to prevent BRD, contact your herd health veterinarian or Elanco representative. To find a representative, please call 1-800-364-2014.
Downloadable Resources
Looking for more information? Access these resources or contact your Elanco representative.
To find a representative, please call 1-800-364-2014
Research Brief
BRD Prevention: A Comparison of Three Vaccination Programs in High-Risk Feedlot Heifers
Important Information
Learn about NUPLURA indications, directions and safety precautions.
Indications
NUPLURA PH+5 has been shown to be effective for the vaccination of healthy cattle, 3 months of age and older, against respiratory disease caused by Mannheimia Haemolytica and disease caused by infectious bovine rhinotracheitis, bovine viral diarrhea virus (Type 1 and Type 2), bovine parainfluenza virus (PI3), and bovine respiratory syncytial virus (BRSV). The duration of immunity for this product has not been established. For more information regarding efficacy and safety data, see productdata.aphis.usda.gov A single dose has been shown to be effective against respiratory disease caused by M. haemolytica as early as 10 days after administration. Safety has been demonstrated in calves 28 days of age and older.
NUPLURA PH+3 has been shown to be effective for the vaccination of healthy cattle, three months of age and older, against respiratory disease caused by M. haemolytica and against disease caused by Infectious Bovine Rhinotracheitis and Bovine Viral Diarrhea Type 1 and 2. The duration of immunity for this product has not been established. For more information regarding efficacy and safety data, see productdata.aphis.usda.gov. A single dose has been shown to be effective against respiratory disease caused by M. haemolytica as early as 10 days after administration. Safety has been demonstrated in calves 28 days of age and older.
For all vaccine products: The label contains complete use information, including cautions and warnings. Always read, understand and follow the label and use directions.
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