NUPLURA PH

NUPLURA® PH+

NUPLURA PH

NUPLURA® PH+ combines the protection of NUPLURA PH and Titanium® in one vaccine, giving herds fast, smooth and powerful protection against Mannheimia haemolytica—the leading cause of Bovine Respiratory Disease (BRD).1 It provides flexible protection against both bacterial and viral pathogens causing BRD, so your animals have the right protection right when they need it.

  • Key Product Benefits:NUPLURA provides protective immunity against M. haemolytica in as few as 10 days after vaccination.
  • It’s easy on cattle with minimal reactivity, including few adverse events or transient injection site swelling2
  • NUPLURA uses recombinant leukotoxoid technology and outer membrane proteins, two virulence factors for protection by advanced technology
  • NUPLURA PH+BVD delivers additional protection against Bovine Viral Diarrhea (BVD) Types 1 and 2
  • NUPLURA PH+3 delivers additional protection against Infectious Bovine Rhinotracheitis (IBR) and BVD Types 1 and 2
  • In one vaccination, NUPLURA PH+ combines the rapid immune response of NUPLURA PH with the powerful viral protection of Titanium

Why Choose NUPLURA?

NUPLURA is the fastest-acting M. haemolytica vaccine available, providing rapid protection against the leading causes of BRD. NUPLURA uses recombinant leukotoxoid technology and outer membrane proteins for a strong immune response.

Fast + Strong
Fast + Strong

NUPLURA provides protective immunity in as few as 10 days after vaccination—the fastest M. haemolytica immunity claim granted on the market.

Fast and strong protection can be used prior to and during periods of elevated stress such as changes in weather, weaning, branding, shipping and commingling.

Smooth + Safe
Smooth + Safe

NUPLURA is safe and gentle on calves as young as 28 days—calves can stay on-feed and have minimal sweats and other setbacks.2

NUPLURA PH+ combines the ease of NUPLURA PH with the powerful protection of Titanium for a smooth, visible difference with minimal swelling at injection sites.2

Flexible + Convenient
Powerful + Advanced Protection

NUPLURA PH+ has demonstrated a significant reduction in lung lesions from 21.69% in the control group to 6.82% in the NUPLURA PH+ group.3

NUPLURA combines two powerful virulence factors for strong and effective protection: recombinant leukotoxoid technology and purified outer membrane proteins that reduce the endotoxin load.

Flexible + Convenient
Flexible + Convenient

NUPLURA PH+ offers options for BRD prevention in one vaccine. Only one vaccination means less stress on the animal and less labor and time to administer.

Deliver The Right Protection When It Matters Most

NUPLURA delivers the fastest protection against M. haemolytica, the leading cause of BRD.

Now add smooth and powerful, and it’s check, check and check.


NUPLURA PH

NUPLURA PH+BVD

ONE SHOT® BVD

NUPLURA PH+3

PYRAMID 3 +

PRESPONSE® SQ


Fast

Days until protective immunity against M. haemolytica

As quick as 10 days

after vaccination

As quick as 10 days

after vaccination

No claim

As quick as 10 days

after vaccination

No claim


Safe

Age-proven safe for use

28 days

28 days

No claim

28 days

No claim


Smooth

Uses only outer membrane proteins, reducing harmful endotoxins

X

X


X



Powerful

Recombinant leukotoxoid for a strong immune response

X

X


X



Respiratory Coverage Effective against

the following

causes of BRD:

M. haemolytica

X

X

X

X

X

BVD Type 1


X

X

X

X


BVD Type 2


X

X

X

X


IBR




X

X



To learn more about how NUPLURA delivers a fast, smooth, powerful and convenient vaccination to prevent BRD, contact your herd health veterinarian or Elanco representative. To find a representative, please call 1-800-364-2014.

About Elanco

Learn why we're a leading provider of innovative solutions that protect and enhance animal health.

Connect with Elanco

Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates. ©2024 Elanco or its affiliates.