Hemicell™️ (β-mannanase)

Hemicell is a diet additive for poultry that maximizes the energy available for growth and performance.

Why Choose Hemicell?

safe to use
Safety Profile

Hemicell is safe to use with other enzyme products.

Increased benefits 
Increased Benefits

The value of Hemicell increases in diets that have high β-mannans content.

Long-lasting control 
Fast-acting

Starts working immediately after ingestion to maximize performance.

Hemicell is a highly specific, patented enzyme for poultry diets. It helps maximize flock performance by mitigating an immune response caused by β-mannans, found in feed ingredients like soybean meal.1-7  

Frequently Asked Questions 

1 Song, W., Wang, G., Chen, L. et al. 1995. “A Receptor Kinase-Like Protein Encoded by the Rice Disease Resistance Gene, Xa21.” Science. 270: 1804-1806.  

2 Beutler, B., Jiang, Z., Georgel, P. et al. 2006. “Genetic Analysis of Host Resistance: Toll-Like Receptor Signaling and Immunity at Large.” Annu. Rev. Immunol. 24: 353-389.   

3 Ausubel, F. 2005. “Are innate immune signaling pathways in plants and animals conserved?” Nature Immunol. 6(10): 973-979.  

4 Didierlaurent, A., Simonet, M. and Sirard, J-C. 2005. “Innate and acquired plasticity of the intestinal immune system.” Cellular and Molecular Life Sciences. 62: 1285-1287.  

5 Stahl, P. and Ezekowitz, R. 1998. “The mannose receptor is a pattern recognition receptor involved in host defense.” Curr. Opin. Immunol. 10(1): 50-55.  

6 Sambrook, I. and Rainbird, A. 1985. “The effect of guar gum and level and source of dietary fat on glucose tolerance in growing pigs.” Brit. J. Nutr. 54(01): 27-35.  

7 Daskiran, M., Teeter, R., Fodge, D. and Hsiao, H. 2004. “An Evaluation of Endo-ß-D-mannanase Hemicell Effects on Broiler Performance and Energy Use in Diets Varying in ß-mannan Content.” Poultry Sci. 83: 662-668.  

8 Hsiao, H., Anderson, D. and Dale, N. 2006. "Levels of β-mannan in Soybean Meal." Poultry Sci. 85: 1430-1432.   

9 Zhang, L. and Tizard, I. (1996). “Activation of a mouse macrophage cell line by acemannan: The major carbohydrate fraction from Aloe vera gel.” Immunopharmacology. 35, 119-128.  

10 Korver, D. 2006. "Overview of the Immune Dynamics of the Digestive System." J. Appl. Poultry Res. 15: 123-135.  

Hemicell,  Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.  

©2023 Elanco or its affiliates. PM-TH-22-0328 

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Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates. ©2023 Elanco.